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Severalcross-sectional studies (some of them large, multicenterstudies with more than 100 MCI subjects) have consis-tently demonstrated that FDG-PET imaging can reli-ably differentiate groups of MCI patients from healthycontrols and on the basis of specific hypometabolic pat-terns (Minoshima et al., 1997; Drzezga et al., 2003, 2005;Del et al., 2008; Nobili et al., 2008). (2001) Attention and fl uctuat-ing attention in patients with dementia with Lewy bodies andAlzheimer disease.